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Overview
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Fervenulin, structurally related to caffeine, was first isolated from Streptomyces fervens in 1959 and reported as a broad spectrum antibiotic, with antineoplastic properties. Fervenulin inhibits egg hatch and increases juvenile mortality of the root-knot nematode Meloidogyne incognita in vitro, killing up to 100% of second-stage nematode juveniles when applied at a concentration of 250 µg/mL.
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