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Overview
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mCherry mRNA with Cap 1 structure, modified by 5mCTP/ψUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Please contact us at for specific academic pricing.
Background
mCherry mRNA encodes the red fluorescent protein mCherry. mCherry is a derivative of the red fluorescent protein DsRed, which is isolated from the sea anemone (Discosoma). mCherry is a monomeric fluorophore with an absorption maximum at 587 nm and an emission maximum at 610 nm. mCherry has good photostability and is widely used for molecular markers and cell component positioning in biology.
This mRNA is capped using a co-transcriptional capping method, which results in the naturally occuring Cap 1 structure with high capping efficiency. It is polyadenylated, modified with 5mCTP/ψUTP and optimized for mammalian systems. The addition of 5mCTP/ψUTP and poly(A) tail can reduce host cell immune response and enhance mRNA stability. It can simulate the function of a fully processed mature mRNA.
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