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DZNep

DZNep

Catalog Number:

I001528190REA

Mfr. No.:

EI-HMT-004

Price:

$424

Size:

1 mg

Quantity:

Add to Cart:

- Overview
  - 3-Deazaneplanocin A; (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-cyclopent-3-ene-1,2-diol; NSC 617989
    
    Potent histone methyltransferase inhibitor which decreases global histone methylation. Inhibits trimethylation of H3K27 and H4K20 in vitro. Selectively induces apoptosis in multiple cancer cell lines with no effect on normal cells. May be used in cocktails to chemically induce pluripotent stem cells (CiPSCs) from somatic cells. Enhances angiogenesis in a mouse model of limb ischemia.
    
    Please contact us at for specific academic pricing.
- Properties
  - Molecular Formula
    
    C12H14N4O3
    
    Molecular Weight
    
    MW=262.3
    
    Appearance
    
    Beige powder
    
    Solubility
    
    Solubilization: May be dissolved in DMSO (20 mg/ml)
    
    Storage
    
    Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month.
    
    * For Research Use Only.
- Applications
  - Application
    
    Epigenetic Inhibitors

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