Name: D-Galactosamine hydrochloride - Synthetic origin
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- Overview
  - D-Galactosamine (GalN) is an aldohexose (2-Amino-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by an amino group (Collins, 2006). Galactosamine (as the N-Acetyl derivative) forms a key part of both N- and O-linked glycoproteins, glycolipids and glycosaminoglycans. Treatment of experimental animals with D-galactosamine / lipopolysaccharide causes lethal liver injury characterized by apoptosis of the hepatocyte and it is used as a laboratory model to study the effect of therapeutic agents (Hirono, 2001).
    
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- Properties
  - Alternative Name
    
    2-Amino-2-deoxy-D-galactopyranose hydrochloride;D-Chondrosamine hydrochloride
    
    CAS Number
    
    1772-03-8
    
    Molecular Formula
    
    C6H13NO5·HCl
    
    Molecular Weight
    
    215.63 g/mol
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Collins (2006) Dictionary of Carbohydrates, Chapman&Hall, A206,
    Hirono et al (2001) Molecular Mechanisms of D-Galactosamine/Lipopolysaccharide-Induced Fulminant Hepatic Failure in Mice and the Effects of Therapeutic Agents. In: Asakura et al (eds.) Trends in Gastroenterology and Hepatology. Springer, Tokyo.