Name: Chemerin-9
Price: 239.00 USD

- Overview
  - Chemokine-like receptor 1 (CMKLR1) agonist.
    Chemerin-9 is a nonapeptide corresponding to amino acids 149-157 of the C terminus of processed chemerin, which retains most of the agonist activity of the full-size protein towards the chemokine-like receptor 1 (CMKLR1) with an EC50 of 7.1 nM. Chemerin-9 significantly suppresses TNF-?-induced mRNA expression of adhesion and pro-inflammatory molecules in human umbilical vein endothelial cells (HUVECs) and significantly attenuates TNF-?-induced adhesion of THP1 monocytes and the macrophage inflammatory phenotype. In Apoe -/- mice, a 4-week infusion of chemerin-9 significantly decreases aortic atherosclerotic lesions.
    
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- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    Chemerin 149-157, Chemerin-9 (human), Chemerin C-terminal peptide
    
    Molecular Formula
    
    C54H66N10O13
    
    Molecular Weight
    
    1063.18
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble to 1 mg/ml in water
    
    Other Properties
    
    Sequence: H-Tyr-Phe-Pro-Gly-Gln-Phe-Ala-Phe-Ser-OH,YFPGQFAFS
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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