Cortistatin 14

Cortistatin 14

Catalog Number:
P004516803LIF
Mfr. No.:
PEPTIDE-SS-020
Price:
$298
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • Endogenous somatostatin like neuropeptide.
          Cortistatin 14 is an endogenous neuropeptide that has structural and functional similarities to somatostatin 14. Cortistatin 14 shows potency at all five somatostatin receptors (sst1 – sst5) and prevents somatostatin 14 from binding to them (IC50 values are 5, 0.09, 0.3, 0.2 and 0.3 nM at sst1, sst2, sst3, sst4 and sst5 receptors respectively). Cortistatin 14 has neuronal depressant and sleep-modulating properties and co-exists with GABA within the cortex and hippocampus. Cortistatin 14 also binds with much lower potency to the ghrelin and ?MRGPRX2 receptors.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          CST-14
          Molecular Formula
          C81H113N19O19S2
          Molecular Weight
          1721.03
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 0.70 mg/ml in water
          Other Properties
          Sequence: H-Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (disulfide bridge between cysteine 2 and cysteine 13),PCKNFFWKTFSSCK
          Modification: Disulfide bridge between cysteine 2 and cysteine 13
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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