CAL-101 (Idelalisib, GS-1101)

CAL-101 (Idelalisib, GS-1101)

Catalog Number:
I002097648UBP
Mfr. No.:
F6181
Price:
$378
  • Size:
    25 mg
    Quantity:
    Add to Cart:
      • Overview
        • CAL-101 (idelalisib or GS-1101) is a potent inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinase (PI3K) with IC50 of 2.5 nM in cell-free assays. CAL-101 decreases pAktS473, pAktT308, and the downstream target S6 in SU-DHL-5, KARPAS-422 and CCRF-SB cells with EC50 of 0.1 to 1.0 μM.

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      • Properties
        • Protein Name
          (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
          Source
          Synthetic
          Formulation
          C22H18FN7O
          Storage
          Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light
          Molecular Weight
          415.42 g/mol

          * Research Use Only

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