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Overview
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Bedaquiline fumarate is the salt form of bedaquiline, a diarylquinoline molecule with an ATP synthetase inhibitory activity. Bedaquiline fumarate is an FDA-approved drug for the oral treatment of multidrug-resistant tuberculosis. Bedaquiline fumarate acts by inhibiting the activity of the ATP synthetase in the pathogenic bacterium Mycobacterium tuberculosis, even in the case of multiple antibiotic resistant strains.
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