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Overview
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Azido-dPEG®4-TFP ester, product number 10567, is a crosslinking compound designed for copper(I)-catalyzed, ruthenium catalyzed, and strain promoted click chemistry. The azide group provides the click chemistry functionality. The 2,3,5,6-tetrafluorophenyl (TFP) ester provides reactivity to primary and secondary amines. The two ends of the molecule are separated by a single molecular weight, discrete polyethylene glycol (dPEG®) spacer. The spacer imparts water solubility to PN10567 and increases the hydrodynamic volume of the molecule. The single molecular weight and discrete chain length of the spacer simplifies analysis of the product and of its conjugates.
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