Login / Register
0

AT6

AT6

Catalog Number:
PTC1441491INV
Mfr. No.:
V3582
Price:
Inquiry
  • Size:
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • AT6 is a novel, potent and highly selective PROTAC-based BRD degrader, it is analog of AT1. Inducing macromolecular interactions with small molecules to activate cellular signaling is a challenging goal. PROTACs (proteolysis-targeting chimeras) are bifunctional molecules that recruit a target protein in proximity to an E3 ubiquitin ligase to trigger protein degradation. Structural elucidation of the key ternary ligase-PROTAC-target species and its impact on target degradation selectivity remain elusive.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          PROTACs
          CAS Number
          2098836-50-9
          Molecular Formula
          C48H58CLN9O7S3
          Molecular Weight
          1004.68
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          CC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[C@@H](CC(NCCOCCOCCSC(C)(C)[C@H](NC(C)=O)C(N3C[C@H](O)C[C@H]3C(NCC4=CC=C(C5=C(C)N=CS5)C=C4)=O)=O)=O)C6=NN=C(C)N67)=C7S1

          * For research use only

    We Also Recommend

    BRD4 degrader AT1

    BRD4 degrader AT1

    BSJ-03-123

    BSJ-03-123

    BSJ-03-123

    BSJ-03-123

    BSJ-4-116

    BSJ-4-116

    Note: If you don't receive our verification email, do the following:

    • Confirm that you entered your email address correctly.
    • Check if the email is in your spam or junk folder.
    • Or you may contact us at .
    • Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.