Artesunate

- Overview
  - Artesunate is an anti-malarial drug and has been found to be effective against multidrug-resistant Plasmodium falciparum and P. vivax malaria. Artesunate has also been found to have anti-cancer activity against leukemia and colon cancer cell lines.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Artesunate causes double stranded breaks in parasite DNA which leads to a buildup of intracellular reactive oxygen species (ROS).
- Properties
  - CAS Number
    
    88495-63-0
    
    Molecular Formula
    
    C19H28O8
    
    Molecular Weight
    
    384.42
    
    Appearance
    
    White crystalline powder
    
    Solubility
    
    Slightly soluble in water, freely soluble in ethanol, acetone, and chloroform
    
    Other Properties
    
    Source: Artemisia annua
    PH: 3.5 - 5.0
    Assay: (HPLC, On dried basis): 98.0% - 102.0%
    Residue On Ignition: Not more than 0.1%
    Heavy Metals: Not more than 20ppm
    Loss on Drying: Not more than 0.5%
    Melting Point: 132°C - 136°C
    Optical Rotation: +4.5 - +6.5
    Identification: Color reaction, IR, HPLC - Passes test
    
    Storage
    
    ≤30°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Artesunate is active against Plasmodium falciparum and P. vivax.