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Overview
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ARCA (Anti Reverse Cap Analog) is a cap analogue with the structure of 3´-O-Me-m7G(5')ppp(5')G, the molecular formula of it is C22H31N10O18P3 (Free acid). The product is used for transcription with T7 RNA polymerase. This product is provided in liquid form. When preparing synthetic mRNA, the cap is often added prior to use in order to stabilize the mRNA and significantly enhance translation. Using a 4:1 mixture of a cap analog to GTP in transcription reactions will cap 80% of the resulting mRNAs.
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Overview
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