Name: Anti-TLR9 antibody
Price: 878.00 USD

Overview
- Recognizes human Toll-like receptor 9. Toll-like receptors (TLRs) are highly conserved fromDrosophila to humans and share structural and functional similarities. TLRs constitute of a family ofpattern recognition receptors (PRRs) that mediate cellular responses to a large variety of pathogens(viruses, bacteria, and parasites) by specific recognition of so-called 'pathogen-associated molecular patterns. Activation of TLRs, a family of at least 11 different members that function either as homo-orheterodimers, leads to activation of NF kappa B-dependent and IFN regulatory factor-dependent signalingpathways. TLRs have a central role in innate immunity and are also required for the development of anadaptive immune response. TLRs are expressed by various cells of the immune system, such asmacrophages and dendritic cells. They recognize and respond to molecules derived from bacterial, viral and fungal pathogens.Immunogen: Purified-fusion protein of extracellular domain of human TLR9 (AA 1-815) and humanIgGFc
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2a
  
  Reactivity
  
  human
  
  Clone
  
  5G5
  
  Immunogen
  
  Purified- fusion protein of extracellular domain of human TLR9 (AA 1-815) and human IgG Fc
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  100 µg purified antibody in Phosphate Buffered Saline containing 0.1% BSA and0.02% sodium azide.
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Concentration
  
  0.1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Toll-Like Receptor 9; Cd Antigen Cd289 (Gene ID:54106; UniProt:Q9NR96)
  
  * For research use only