Name: Anti-SIRT1 antibody
Price: 297.00 USD

Overview
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 448-747 of human SIRT1 (NP_036370. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Nad-Dependent Protein Deacetylase Sirtuin-1; Hsirt1; Nad-Dependent Protein Deacylase Sirtuin-1; Regulatory Protein Sir2 Homolog 1; Sir2-Like Protein 1; Hsir2 Cleaved Into-Sirtt1 75 Kda Fragment; 75sirt1 (Gene ID:23411; UniProt:Q96EB6)
  
  * For research use only