![Immunofluorescence analysis of NIH-3T3 treated by chloroquine and NIH-3T3 cells using [KO Validated] LC3B Rabbit pAb (STJ113754) at dilution of 100 (40x lens).NIH/3T3 cells were treated by Chloroquine (50 μM) for 20 hours(left). Blue: DAPI for nuclear staining.](https://resource.amerigoscientific.com/p-img/STJ113754_3_IF__09176.1602778497.jpg)
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Overview
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The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
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