Anti-SELP antibody

Catalog Number:

A001021350STJ

Mfr. No.:

STJ114386

Price:

$297

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Overview
- This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 220-319 of human SELP (NP_002996. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  P-Selectin; Cd62 Antigen-Like Family Member P; Granule Membrane Protein 140; Gmp-140; Leukocyte-Endothelial Cell Adhesion Molecule 3; Lecam3; Platelet Activation Dependent Granule-External Membrane Protein; Padgem; Cd Antigen Cd62p (Gene ID:6403; UniProt:P16109)
  
  * For research use only