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Overview
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The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded mouse heart using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse liver using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat liver using SET antibody (STJ114376) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using SET antibody (STJ114376) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-SET antibody
Anti-SET antibody
Catalog Number:
A001021342STJ
Mfr. No.:
STJ114376
Price:
$297
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