Anti-S100A12 antibody

Catalog Number:

A001021339STJ

Mfr. No.:

STJ114373

Price:

$297

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Overview
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A12 (NP_005612. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Protein S100-A12; Cgrp; Calcium-Binding Protein In Amniotic Fluid 1; Caaf1; Calgranulin-C; Cagc; Extracellular Newly Identified Rage-Binding Protein; En-Rage; Migration Inhibitory Factor-Related Protein 6; Mrp-6; P6; Neutrophil S100 Protein; S100 Calcium-Binding Protein A12 Cleaved Into-Calcitermin (Gene ID:6283; UniProt:P80511)
  
  * For research use only