Anti-PSAP antibody

Anti-PSAP antibody

Catalog Number:
A001034789STJ
Mfr. No.:
STJ25165
Price:
$390
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      • Overview
        • This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 60-310 of human PSAP (NP_002769. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Prosaposin; Proactivator Polypeptide Cleaved Into-Saposin-A; Protein A-Saposin-B-Val-Saposin-B; Cerebroside Sulfate Activator; Csact; Dispersin; Sphingolipid Activator Protein 1; Sap-1; Sulfatide/Gm1 Activator-Saposin-C; A1 Activator; Co-Beta-Glucosidase; Glucosylceramidase Activator; Sphingolipid Activator Protein 2; Sap-2-Saposin-D; Component C; Protein C (Gene ID:5660; UniProt:P07602)

          * For research use only

      • Applications
        • Application
          WB; IHC; IF
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200
          IF 1:50-1:200

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