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Overview
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
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Overview
Immunofluorescence analysis of U2OS cells using PSMA2 antibody (STJ25171). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PSMA2 antibody (STJ25171) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-PSMA2 antibody
Anti-PSMA2 antibody
Catalog Number:
A001034792STJ
Mfr. No.:
STJ25171
Price:
$297
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