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Overview
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The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
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Overview
Western blot analysis of extracts of HeLa cells, using Phospho-FLNA-S2152 pAb (STJ117881) at 1:1000 dilution or FLNA antibody (STJ110205).Hela cell lysate were treated by CIP (20ul CIP for each 400ul cell lysate) at 37°C for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.Detection: ECL Enhanced Kit.Exposure time: 30s.
Western blot analysis of extracts of C6 cells, using Phospho-FLNA-S2152 antibody (STJ117881) at 1:1000 dilution.C6 cell lysate were treated by CIP (20ul CIP for each 400ul cell lysate) at 37°C for 1 hour .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.Detection: ECL Enhanced Kit.Exposure time: 30s.
Anti-Phospho-FLNA-(S2152) antibody
Anti-Phospho-FLNA-(S2152) antibody
Catalog Number:
A001024722STJ
Mfr. No.:
STJ117881
Price:
$295
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