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Overview
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PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
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Overview
Immunofluorescence analysis of A549 cells using PAX2 antibody (STJ24908). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PAX2 antibody (STJ24908) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-PAX2 antibody
Anti-PAX2 antibody
Catalog Number:
A001034630STJ
Mfr. No.:
STJ24908
Price:
$297
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