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Overview
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This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human lung cancer using PAX3 antibody (STJ115865) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using PAX3 antibody (STJ115865) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of 293T cells, using PAX3 antibody (STJ115865) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-PAX3 antibody
Anti-PAX3 antibody
Catalog Number:
A001022744STJ
Mfr. No.:
STJ115865
Price:
$297
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