Name: Anti-NGFR antibody
Price: 337.00 USD

Overview
- Nerve growth factor receptor (p75NGFR), is the first of neurotrophin receptors to be isolated and is a member of the tumor necrosis factor (TNF) receptor family. NGFR has been shown to be a reliable marker for desmoplastic and neurotropic melanoma by several groups. It is now apparent that expression of NGFR is ubiquitous and not limited to the nervous system, being expressed in mature nonneural cells such as perivascular cells, follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells and myoepithelial cells. Studies in prostate and urothelial cancer suggest that NGFR may act as a tumor suppressor, negatively regulating cell growth and proliferation. Anti‐NGFR labels the myoepithelial cells of breast ducts and intralobular fibroblasts of breast ducts and thus aides in the diagnosis of malignancy in the breast.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2b kappa
  
  Reactivity
  
  human
  
  Clone
  
  ZM55
  
  Immunogen
  
  Recombinant human p75 NGFR protein fragment (around aa 281‐421)
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
  
  Storage
  
  Store at 2-8°C for up to 1 year
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Tumor Necrosis Factor Receptor Superfamily Member 16; Gp80-Lngfr; Low Affinity Neurotrophin Receptor P75ntr; Low-Affinity Nerve Growth Factor Receptor; Ngf Receptor; P75 Icd; Cd Antigen Cd271 (Gene ID:4804; UniProt:P08138)
  
  * For research use only