Name: Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)
Price: 680.00 USD

- Overview
  - Antigen Distribution: B cells and T cells (upregulated upon activation), macrophages, dendritic cells, and astrocytes
    Specificity: Anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) recognizes an epitope on Mouse CD86
    Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
    Isotype Control: Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
    Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
    Aggregation: Aggregation level ≤ 5%
    
    Please contact us at for specific academic pricing.
    
    Background
    
    CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the Ig gene superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counterreceptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses in vivo and in vitro.
- Properties
  - Host
    
    rat
    
    Isotype
    
    IgG2a kappa
    
    Reactivity
    
    mouse
    
    Clone
    
    GL1
    
    Immunogen
    
    LPS-activated CBA/Ca mouse splenic B cells
    
    Purification
    
    >95% by SDS-PAGE and HPLC
    
    Formulation
    
    0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
    
    Storage
    
    anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
    
    Molecular Weight
    
    1.0 mg/ml
    
    Regulatory Status
    
    Each investigator should determine their own optimal working dilution for specific applications.
    
    Antigen
    
    (Gene ID:Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1)
    
    * Products are for research use only. Not for use in diagnostic or therapeutic procedures.
- Applications
  - Application
    
    Flow Cytometry; Immunoprecipitation; IHC (frozen); Immunocytochemistry; Blocking; Immunofluorescence; WB; CyTOF

Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)

Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)

Background

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