Name: Anti-Mouse CD80 In Vivo Antibody - Low Endotoxin (16-10A1)
Price: 680.00 USD

- Overview
  - Antigen Distribution: Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells.
    Specificity: Anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80
    Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
    Isotype Control: Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
    Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
    Aggregation: Aggregation level ≤ 5%
    
    Please contact us at for specific academic pricing.
    
    Background
    
    CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
- Properties
  - Host
    
    armenian hamster
    
    Isotype
    
    IgG
    
    Reactivity
    
    mouse
    
    Clone
    
    16-10A1
    
    Immunogen
    
    Purified Recombinant Mouse CD80 (>98%)
    
    Purification
    
    >95% by SDS-PAGE and HPLC
    
    Formulation
    
    0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
    
    Storage
    
    anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
    
    Molecular Weight
    
    1.0 mg/ml
    
    Regulatory Status
    
    Each investigator should determine their own optimal working dilution for specific applications.
    
    Antigen
    
    (Gene ID:Activation B7-1 antigen, B7)
    
    * Products are for research use only. Not for use in diagnostic or therapeutic procedures.
- Applications
  - Application
    
    Immunoprecipitation; WB; Blocking; Flow Cytometry; IHC (frozen)

Anti-Mouse CD80 In Vivo Antibody - Low Endotoxin (16-10A1)

Anti-Mouse CD80 In Vivo Antibody - Low Endotoxin (16-10A1)

Background

We Also Recommend

Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin (145-2C11)

Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin (500A2)

Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)