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Overview
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This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
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Overview
Immunohistochemistry of paraffin-embedded mouse stomach using LDHB antibody (STJ29762) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using LDHB antibody (STJ29762) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-LDHB antibody
Anti-LDHB antibody
Catalog Number:
A001037706STJ
Mfr. No.:
STJ29762
Price:
$297
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