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Overview
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Specifically recognizes simple and glandular epithelial cells from the gastrointestinal tract, the respiratory tract and the urogenital tract, as well as endocrine and exocrine tissues andmyoepithelial cells. No reaction with stratified squamous epithelia. In the transitional epithelium of thebladder RGE 53 reacts only with superficial (umbrella) cells.The antibody is useful for the discriminationof adenocarcinomas and mesotheliomas from squamous cell carcinomas and non-epithelial tumors.Polypeptide reacting: 45 kD keratin K18 (formerly also designated cytokeratin 18.Immunogen: isolated from HeLa cells
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