-
-
Overview
-
Recognizes a phosphorylated epitope on heavy neurofilament protein (210 kDa) of variousspecies. Antibodies to the various neurofilament subunits are very useful cell type markers since theproteins are among the most abundant of the nervous system, are expressed only in neurons and arebiochemically very stable. Neurofilaments (NFs) are a type of intermediate filaments (IF) expressedalmost exclusively in neuronal cells, and in those cells most prominently in large axons. NFs in mostvertebrates are composed of three different polypeptide chains with different molecular weights ìneurofilament heavy protein (NF-H), medium (NF-M) and light protein (NF-L), which share sequenceand structural similarity in a coiled-coil core domain, but differ in the length and sequence of their N-termini and more dramatically of their C-termini which in the case of NF-M and NF-H form the flexibleextensions that link NFs to each other and to other elements in the cytoplasm.Immunogen: Pellet of porcine brain cold-stable proteins after depolymerization of microtubules.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview
Anti-Neurofilament antibody
Anti-Neurofilament antibody
Catalog Number:
IGA1028068STJ
Mfr. No.:
STJ16100237
Price:
$739
Size:
0.1 mg
Quantity:
Add to Cart:
.