Anti-Kappa Light Chains antibody

Anti-Kappa Light Chains antibody

Catalog Number:
IGA1028211STJ
Mfr. No.:
STJ16100380
Price:
$851
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      • Overview
        • Detects surface immunoglobulin on normal and neoplastic B-cells. In paraffin-embeddedtissue, anti-kappa exhibits strong staining of kappa-positive plasma cells and cells that have absorbedexogenous immunoglobulins. When dealing with B-cell neoplasms, the determination of light chainratios remains the centerpiece. Most B-cell lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda positive cells. If only a singlelight chain type is detected, a lymphoproliferative disorder exists. Monoclonality is determined by akappa-lambda ratio of greater than or equal to 3:1 or a lambda-kappa ratio greater than 2:1.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1 kappa
          Reactivity
          human
          Clone
          L1C1
          Conjugate
          Unconjugated
          Formulation
          1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
          Storage
          Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
          Regulatory Status
          RUO

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC 1:100 – 1:500

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