Anti-Human Cytomegalovirus antibody

Anti-Human Cytomegalovirus antibody

Catalog Number:
IGA1028282STJ
Mfr. No.:
STJ16100451
Price:
$1,588
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      • Overview
        • Human cytomegalovirus (CMV) is a beta-herpesvirus (human herpesvirus 5) that causes widespreadpersistent infection. CMV continues to be an important opportunistic pathogen inimmunocompromised patients. It is estimated that 30% of transplant recipients experience CMVdisease. The range of organ involvement in post-transplant CMV disease is wide; hepatitis occurs in40% of liver transplant recipients, and pneumonitis is more frequently seen in heart and heart-lungtransplant patients. Other organs that are commonly affected are the gastrointestinal tractand the peripheral and central nervous systems. Histologic diagnosis of CMV in fixed tissues usuallyrests on identifying characteristic cytopathic effects including intranuclear inclusions, cytoplasmicinclusions, or both, especially in the endothelial cells. However, histologic examination lacks sensitivity, and in some cases atypical cytopathic features can be confused with reactive or degenerative changes.

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      • Properties
        • Host
          mouse
          Antibody Type
          mix
          Isotype
          IgG2a
          Reactivity
          human
          Clone
          8B1.2, 1G5.2 and 2D4.2
          Conjugate
          Unconjugated
          Formulation
          1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
          Storage
          Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
          Regulatory Status
          RUO

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC 1:25 – 1:50

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