Name: Anti-CD23 antibody
Price: 224.00 USD

Overview
- CD23 is a protein encoded by the FCER2 gene which is approximately 36, 4 kDa. CD23 is localised to the cell membrane. It is involved in cytokine signalling in immune system, notch2 activation, transmission of signals to the nucleus and B-cell development pathways. It is a B-cell specific antigen and a low-affinity receptor for IgE. It has essential roles in B-cell growth and differentiation, and the regulation of IgE production. It can also exists in a soluble secreted form which functions as a potent mitogenic growth factor. CD23 is expressed in the blood, lymph nodes and spleen. Mutations in the FCER2 gene may result in chronic conjunctivitis. STJ96951 was developed from clone 1E9 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous CD23 proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human; mouse; rat
  
  Clone
  
  1E9
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Low Affinity Immunoglobulin Epsilon Fc Receptor; Blast-2; C-Type Lectin Domain Family 4 Member J; Fc-Epsilon-RII; Immunoglobulin E-Binding Factor; Lymphocyte Ige Receptor; Cd Antigen Cd23 [Cleaved Into-Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form-Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form] (Gene ID:2208; UniProt:P06734)
  
  * For research use only