Anti-Human CD71 antibody

Anti-Human CD71 antibody

Catalog Number:
IGA1028285STJ
Mfr. No.:
STJ16100454
Price:
$1,422
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      • Overview
        • CD71, also known as transferrin receptor, is a membrane glycoprotein that mediates the uptake of ironfrom transferrin for hemoglobin synthesis in erythroid cells. Early erythroid precursors anderythroblasts contain the highest mass of transferrin receptors, and expression is lost as these cellscease hemoglobin synthesis and mature into erythrocytes. Therefore, anti-CD71 is a useful marker forhighlighting erythroid precursors in bone marrow specimens.Increased CD71 expression is also associated with active cell growth including neoplastic tumor growthand may be seen in various carcinomas such as thyroid carcinomas, lung carcinomas, breastcarcinomas, hepatocellular carcinomas and colorectal carcinomas.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          MRQ-48
          Conjugate
          Unconjugated
          Formulation
          1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
          Storage
          Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
          Regulatory Status
          RUO

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC 1:100 – 1:500

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