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Overview
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Reacts with a polymorphic determinant on HLA-DR molecules which is associated with DR3, DR5, and DRw6 (DRw52-like). It does not react with DRw8. The antibody reacts with part of the HLA-Dmolecules (29+34 kD). The determinant is strongly expressed on DR3 positive cells and more weakly onDR5 and DRw6 positive cells. The antibody is useful for HLA-DR typing and biochemical characterizationof the DR52w positive molecules and functional studies. Cross reacts with Chimpanzee, Macaca-apesand gorilla.
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