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Overview
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This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Immunoprecipitation analysis of 200ug extracts of K562 cells using 1ug HDAC2 antibody (STJ23929). Western blot was performed from the immunoprecipitate using HDAC2 antibody (STJ23929) at a dilition of 1:1000.
Immunofluorescence analysis of A549 cells using HDAC2 antibody (STJ23929). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse heart using HDAC2 antibody (STJ23929) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophageal cancer using HDAC2 antibody (STJ23929) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using HDAC2 antibody (STJ23929) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using HDAC2 antibody (STJ23929) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-HDAC2 antibody
Anti-HDAC2 antibody
Catalog Number:
A001034082STJ
Mfr. No.:
STJ23929
Price:
$297
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