Name: Anti-DOG1 antibody
Price: 331.00 USD

Overview
- In normal breast tissue, 304‐1A5 and 31A5 labels breast ductal and lobular epithelial cells. In tumor cells, it is reactive with all types of breast adenocarcinoma regardless tumor differentiation and types. Adenocarcinomas from other organs rarely express mammaglobin. Cellular localization: cytoplasmic. Mammaglobin is a breast‐associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Unlike other secretoglobin family members, mammaglobin mRNA expression is breast specific, which has been shown to be a very sensitive marker of occult breast cancer cells in sentinel lymph nodes (Figure 1) and peripheral blood. By paraffin immunohistochemistry, the overall sensitivity of mammaglobin for breast cancers (Figure 2) was reported about 80%. When combined with other breast‐restricted markers such as GCDFP‐15, an overall sensitivity of 84% could be achieved (10). Mammaglobin can play a contributing role in the identification of primary sites of carcinomas presenting at metastatic sites. Positive control: normal human breast tissue.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1 kappa
  
  Reactivity
  
  human
  
  Clone
  
  DOG1.1
  
  Immunogen
  
  Synthetic peptides FLJ34272 specific to human gastrointestinal stromal tumor (GIST)
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
  
  Storage
  
  Store at 2-8°C for up to 1 year
  
  Regulatory Status
  
  RUO
  
  * For research use only