Anti-DNMT3A antibody

Catalog Number:

A001033781STJ

Mfr. No.:

STJ23412

Price:

$297

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Overview
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human DNMT3A (NP_715640. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Dna; Cytosine-5-Methyltransferase 3a; Dnmt3a; Dna Methyltransferase HsaIIIa; Dna Mtase HsaIIIa; M.hsaIIIa (Gene ID:1788; UniProt:Q9Y6K1)
  
  * For research use only