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Overview
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Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
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- Properties
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Overview
Immunofluorescence analysis of HeLa cells using DCK antibody (STJ23344). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded rat kidney using DCK antibody (STJ23344) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using DCK antibody (STJ23344) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using DCK Antibody (STJ23344) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-DCK antibody
Anti-DCK antibody
Catalog Number:
A001033735STJ
Mfr. No.:
STJ23344
Price:
$297
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