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Overview
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This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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- Properties
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Overview
Immunofluorescence analysis of Jurkat cells using CD4 antibody (STJ114878) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Mouse thymus using CD4 antibody (STJ114878) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Rat thymus cells using CD4 antibody (STJ114878) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of U-937 cells, using CD4 antibody (STJ114878) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-CD4 antibody
Anti-CD4 antibody
Catalog Number:
A001021808STJ
Mfr. No.:
STJ114878
Price:
$297
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