Name: Anti-CD4 antibody
Price: 632.00 USD

Overview
- Reacts with a 59 kD glycoprotein specific for the CD4 antigen, which functions as a receptorfor MHC class II and for HIV. The antigen is characteristic for helper T-cells. The specificity wasconfirmed by testing with CD4 cDNA transfected cells, with purified CD4 antigen and competitionstudies with other CD4 antibodies.CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class IImolecules) and HIV infection (human immunodeficiency virus; CD4 is primary receptor for HIV-1surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell differentiation, T-cell selection and signal transduction.Immunogen: Human thymocytes and T lymphocytes.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2a
  
  Reactivity
  
  human
  
  Clone
  
  MEM-115
  
  Immunogen
  
  Human thymocytes and T lymphocytes
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  100 µg of affinity purified antibody in PBS containing 15 mM sodium Azide, pH 7.4.: 1 mg/ml
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  T-Cell Surface Glycoprotein Cd4; T-Cell Surface Antigen T4/Leu-3; Cd Antigen Cd4 (Gene ID:920; UniProt:P01730)
  
  * For research use only