Name: Anti-CD25 antibody
Price: 1037.00 USD

- Overview
  - CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and Blymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gammachain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and theIL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains resultin low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. Theexpression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory modefor controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2plays an important role as a growth factor, differentiation factor, and regulator of cell death. IL-2stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocytemacrophage colony formation. The targeted disruption of a similar gene in mice leads to ulcerativecolitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations inthis gene are associated with interleukin 2 receptor alpha deficiency.Immunogen: Human CD25
    
    Please contact us at for specific academic pricing.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Reactivity
    
    human
    
    Clone
    
    CD25-3G10
    
    Immunogen
    
    Human CD25
    
    Conjugate
    
    PE
    
    Formulation
    
    0.5 ml purified antibody, conjugated to R-PE, in Phosphate Buffer Saline solution containing sucrose, 4 mg/ml BSA and 0.1% sodium azide.
    
    Storage
    
    Store antibody at 2-8°C until expiry. Avoid prolonged exposure to light.
    
    Concentration
    
    approximately 0.1 mg/ml
    
    Regulatory Status
    
    RUO
    
    * For research use only
- Applications
  - Application
    
    Flow Cytometry