Anti-CD25 antibody

Anti-CD25 antibody

Catalog Number:
A001052378STJ
Mfr. No.:
STJ97009
Price:
$224
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      • Overview
        • CD25 is a protein encoded by the IL2RA gene which is approximately 30, 8 kDa. CD25 is localised to the cell membrane. It is involved in RET signalling, apoptotic pathways in synovial fibroblasts, PEDF induced signalling and the TGF-beta pathway. It is a proteinaceous signalling compound that is a major mediator of the immune response. It controls many different cellular functions including proliferation, differentiation, cell survival and apoptosis but is also involved in several pathophysiological processes. CD25 is expressed in the blood, spleen and lymph nodes. Mutations in the IL2RA gene may result in intermediate uveitis. STJ97009 was developed from clone Q22 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous human CD25 protein.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          Q22
          Immunogen
          Synthetic Peptide
          Purification
          The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Interleukin-2 Receptor Subunit Alpha; Il-2 Receptor Subunit Alpha; Il-2-Ra; Il-2r Subunit Alpha; Il2-Ra; Tac Antigen; P55; Cd Antigen Cd25 (Gene ID:3559; UniProt:P01589)

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC 1:200

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