Name: Anti-CD38 antibody
Price: 874.00 USD

- Overview
  - CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid andlymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosylcyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor.Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells(i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in celladhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in thepancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.Immunogen: Human CD38
    
    Please contact us at for specific academic pricing.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Reactivity
    
    human
    
    Clone
    
    HIT2
    
    Immunogen
    
    Human CD38
    
    Conjugate
    
    FITC
    
    Formulation
    
    0.5 ml purified antibody, conjugated to FITC, in Phosphate Buffer Saline solution containing 4-5 mg/ml BSA and 0.1% sodium azide.
    
    Storage
    
    Store antibody at 2-8°C until expiry. Avoid prolonged exposure to light.
    
    Concentration
    
    approximately 0.4 mg/ml
    
    Regulatory Status
    
    RUO
    
    Antigen
    
    Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1; 2'-Phospho-Adp-Ribosyl Cyclase; 2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase; 2'-Phospho-Cyclic-Adp-Ribose Transferase; Adp-Ribosyl Cyclase 1; Adprc 1; Cyclic Adp-Ribose Hydrolase 1; Cadpr Hydrolase 1; T10; Cd Antigen Cd38 (Gene ID:952; UniProt:P28907)
    
    * For research use only
- Applications
  - Application
    
    Flow Cytometry