Anti-CD2 antibody

Catalog Number:

A001052340STJ

Mfr. No.:

STJ96971

Price:

$224

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Overview
- CD2 is a protein encoded by the CD2 gene which is approximately 39, 4 kDa. CD2 is localised to the cell membrane. It is involved in PEDF induced signalling, the TGF-beta pathway, Akt signalling and ERK signalling. It is a surface antigen found on all peripheral blood T-cells. It interacts with LFA3 on antigen presenting cells to optimize immune recognition. CD2 is implicated in the triggering of T-cells with the cytoplasmic domain is implicated in the signalling function. CD2 is expressed in the spleen, pancreas, blood, kidney and lymph nodes. Mutations in the CD2 gene may result in immune defects. STJ96971 was developed from clone 3F3 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous CD2 proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human; mouse; rat
  
  Clone
  
  3F3
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  T-Cell Surface Antigen Cd2; Erythrocyte Receptor; Lfa-2; Lfa-3 Receptor; Rosette Receptor; T-Cell Surface Antigen T11/Leu-5; Cd Antigen Cd2 (Gene ID:914; UniProt:P06729)
  
  * For research use only