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Overview
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Calponin is a 34-kD actin filament-associated regulatory protein that interacts with actin, tropomyosin, and calmodulin. It is involved in the smooth muscle contraction mechanism and is restricted exclusivelyto smooth muscle tissue and myoepithelial cells. Anti-calponin has been found to be useful marker fordifferentiating benign sclerosing lesions of the breast from invasive carcinoma.
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