Name: Anti-C3a antibody
Price: 297.00 USD

Overview
- Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1364-1663 of human C3 (NP_000055. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Complement C3; C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 1 Cleaved Into-Complement C3 Beta Chain-C3-Beta-C; C3bc-Complement C3 Alpha Chain-C3a Anaphylatoxin-Acylation Stimulating Protein; Asp; C3adesarg-Complement C3b Alpha' Chain-Complement C3c Alpha' Chain Fragment 1-Complement C3dg Fragment-Complement C3g Fragment-Complement C3d Fragment-Complement C3f Fragment-Complement C3c Alpha' Chain Fragment 2 (Gene ID:718; UniProt:P01024)
  
  * For research use only