Name: Anti-CD68 antibody
Price: 224.00 USD

Overview
- CD68 is a protein encoded by the CD68 gene which is approximately 37, 4 kDa. CD68 short isoform is localised to the cell membrane and the long isoform is localised to the endosome membrane. It is involved in the innate immune system, stem cell differentiation pathways and lineage-specific markers. This protein falls under the lysosomal/endosomal-associated membrane glycoprotein family. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue-and organ-specific lectins or selectins. It is also a member of the scavenger receptor family which typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. CD68 is highly expressed by blood monocytes and tissue macrophages. Mutations in the CD68 gene may result in a granular cell tumour. STJ96952 was developed from clone 6F3 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous CD68 proteins.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human; mouse; rat
  
  Clone
  
  6F3
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Macrosialin; Gp110; Cd Antigen Cd68 (Gene ID:968; UniProt:P34810)
  
  * For research use only