AEC5

AEC5

Catalog Number:
P004516977LIF
Mfr. No.:
PEPTIDE-PT-109
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  • Size:
    1mg
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      • Overview

        • Lipopeptoid with antifungal activity against Cryptococcus neoformans.
          AEC5 is a trimeric lipopeptoid with potent antifungal activity against Cryptococcus neoformans and Cryptococcus gattii and modest efficacy against other microbial pathogens. AEC5 rapidly reduces fungal burden in infected macrophages against C. neoformans, with nearly 50% reduction in fungal growth after 30 minutes and complete elimination of viable fungi within 3 hours. In mouse models AEC5 has an in vivo half-life of >20 hours and no observable toxicity following 28 days of daily injections.

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      • Properties
        • Categories
          Peptoids
          Molecular Formula
          C28H51N5O4
          Molecular Weight
          521.7
          Appearance
          Freeze dried solid
          Purity
          96.2% by HPLC
          Solubility
          >50 mg per ml in water
          Other Properties
          Sequence: Ntri-NLys-Nfur,Ntri-NLys-Nfur
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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