Aclarubicin - Amerigo Scientific

- Overview
  - Aclarubicin (aclacinomycin A) is an anthracycline and topoisomerase II inhibitor that has been clinically tested against haematologic and solid tumors. Aclarubicin stabilizes topoisomerase I cleavage. Aclarubicin accumulates efficiently in the mitochondria of living human cells and leads to mitochondrial dysfunction. Aclarubicin inhibits reverse transcriptase, endothelin converting enzyme and collagenase, and is active against HIV.
    
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- Properties
  - CAS Number
    
    57576-44-0
    
    Molecular Formula
    
    C42H53NO15
    
    Molecular Weight
    
    811.9
    
    Appearance
    
    Red solid
    
    Solubility
    
    Soluble in methanol or DMSO
    
    Other Properties
    
    Source: Streptomyces sp.
    
    * For research use only