6xHis-Ube2D1 (UbcH5A)

- Overview
  - Ube2D1 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Two other homologues of Ube2D1 exist called Ube2D2 and Ube2D3. Ube2D2 is 89% identical to the amino acid sequence of Ube2D1 ad Ube2D3 is 88% identical. Ube2D1 has been linked to cadminum toxicity. It might also play a role in LDL cholesterol receptor ubiquitination in an Idol-dependent fashion.
    
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- Properties
  - Protein Name
    
    USFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1
    
    Source
    
    Bacterial recombinant
    
    Formulation
    
    20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
    
    Storage
    
    Store at -80°C; avoid multiple freeze-thaw cycles
    
    Concentration
    
    See tube label
    
    Molecular Weight
    
    16.6 kDa
    
    Sequence
    
    NCBI RefSeq: NM_003338
    
    * Research Use Only